PDB Information

PDB5AQI
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Jones, A.M., Westwood, I.M., Osborne, J.D., Matthews, T.P., Cheeseman, M.D., Rowlands, M.G., Jeganathan, F., Burke, R., Lee, D., Kadi, N., Liu, M., Richards, M., McAndrew, C., Yahya, N., Dobson, S.E., Jones, K., Workman, P., Collins, I., van Montfort, R.L.
Sci Rep
HeaderChaperone
Released2015-09-22
Resolution1.980
CATH Insert Date16 Oct, 2016

PDB Images (15)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 17 Oct, 2016 Chopped
B 17 Oct, 2016 Chopped
C 17 Oct, 2016 Chopped
D 17 Oct, 2016 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
5aqiA01 25 Oct, 2016 3.30.420.40 Assigned
5aqiA02 25 Oct, 2016 3.30.30.30 Assigned
5aqiA03 25 Oct, 2016 3.30.420.40 Assigned
5aqiA04 25 Oct, 2016 3.90.640.10 Assigned
5aqiB00 22 Oct, 2016 1.20.58.120 Assigned
5aqiC01 25 Oct, 2016 3.30.420.40 Assigned
5aqiC02 25 Oct, 2016 3.30.30.30 Assigned
5aqiC03 25 Oct, 2016 3.30.420.40 Assigned
5aqiC04 25 Oct, 2016 3.90.640.10 Assigned
5aqiD00 22 Oct, 2016 1.20.58.120 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein