PDB 5acb

PDB Information

PDB5ACB
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Covalent Targeting of Remote Cysteine Residues to Develop Cdk12 and Cdk13 Inhibitors.
Zhang, T., Kwiatkowski, N., Olson, C.M., Dixon-Clarke, S.E., Abraham, B.J., Greifenberg, A.K., Ficarro, S.B., Elkins, J.M., Liang, Y., Hannett, N.M., Manz, T., Hao, M., Bartkowiak, B., Greenleaf, A.L., Marto, J.A., Geyer, M., Bullock, A.N., Young, R.A., Gray, N.S.
Nat.Chem.Biol.
HeaderTransferase
Released2015-08-14
Resolution2.700
CATH Insert Date07 Aug, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 Aug, 2016 Chopped
B 08 Aug, 2016 Chopped
C 08 Aug, 2016 Chopped
D 08 Aug, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
5acbA01 01 Sep, 2016 1.10.472.10 Assigned
5acbA02 01 Sep, 2016 1.10.472.10 Assigned
5acbB01 01 Sep, 2016 1.10.472.10 Assigned
5acbB02 01 Sep, 2016 1.10.472.10 Assigned
5acbC01 01 Sep, 2016 3.30.200.20 Assigned
5acbC02 01 Sep, 2016 1.10.510.10 Assigned
5acbD01 01 Sep, 2016 3.30.200.20 Assigned
5acbD02 01 Sep, 2016 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O75909 CCNK_HUMAN Homo sapiens Cyclin-K
O75909 CCNK_HUMAN Homo sapiens Cyclin-K
Q9NYV4 CDK12_HUMAN Homo sapiens Cyclin-dependent kinase 12
Q9NYV4 CDK12_HUMAN Homo sapiens Cyclin-dependent kinase 12