PDB 5aaf

PDB Information

PDB5AAF
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
7-(Pyrazol-4-Yl)-3H-Imidazo[4,5-B]Pyridine-Based Derivatives for Kinase Inhibition: Co-Crystallisation Studies with Aurora-A Reveal Distinct Differences in the Orientation of the Pyrazole N1-Substituent.
Bavetsias, V., Perez-Fuertes, Y., Mcintyre, P.J., Atrash, B., Kosmopoulou, M., O'Fee, L., Burke, R., Sun, C., Faisal, A., Bush, K., Avery, S., Henley, A., Raynaud, F.I., Linardopoulos, S., Bayliss, R., Blagg, J.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2015-07-24
Resolution2.780
CATH Insert Date20 Sep, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Sep, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5aafA01 30 Sep, 2015 3.30.200.20 Assigned
5aafA02 30 Sep, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A