PDB Information

PDB5A86
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Identification and Optimization of Benzimidazole Sulfonamides as Orally Bioavailable Sphingosine 1-Phosphate Receptor 1 Antagonists with in Vivo Activity.
Hennessy, E.J., Oza, V.B., Adam, A., Byth, K., Castriotta, L., Grewal, G., Hamilton, G., Kamhi, V.M., Lewis, P., Li, D., Lyne, P.D., Oster, L., Rooney, M.T., Saeh, J.C., Sha, L., Su, Q., Wen, S., Xue, Y., Yang, B.
J.Med.Chem.
HeaderSignaling Protein
Released2015-07-13
Resolution2.250
CATH Insert Date08 Nov, 2015

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 09 Nov, 2015 Chopped
B 09 Nov, 2015 Chopped
C 09 Nov, 2015 Rejected
D 09 Nov, 2015 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5a86A00 18 Nov, 2015 1.10.565.10 Assigned
5a86B00 23 Nov, 2015 1.10.565.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q15788 NCOA1_HUMAN Homo sapiens Nuclear receptor coactivator 1
O75469 NR1I2_HUMAN Homo sapiens Nuclear receptor subfamily 1 group I member 2
Q15788 NCOA1_HUMAN Homo sapiens Nuclear receptor coactivator 1
O75469 NR1I2_HUMAN Homo sapiens Nuclear receptor subfamily 1 group I member 2
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