PDB Information

PDB5A5S
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Fragment-Based Discovery of Low-Micromolar Atad2 Bromodomain Inhibitors.
Demont, E.H., Chung, C., Furze, R.C., Grandi, P., Michon, A., Wellaway, C., Barrett, N., Bridges, A.M., Craggs, P.D., Diallo, H., Dixon, D.P., Douault, C., Emmons, A.J., Jones, E.J., Karamshi, B.V., Locke, K., Mitchell, D.J., Mouzon, B.H., Prinjha, R.K., Roberts, A.D., Sheppard, R.J., Watson, R.J., Bamborough, P.
J.Med.Chem.
HeaderHydrolase
Released2015-06-20
Resolution1.360
CATH Insert Date16 Aug, 2015

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 17 Aug, 2015 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5a5sA01 24 Aug, 2015 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4