PDB 4zy2

PDB Information

PDB4ZY2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum FcB1/Columbia
Primary Citation
Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Drinkwater, N., Vinh, N.B., Mistry, S.N., Bamert, R.S., Ruggeri, C., Holleran, J.P., Loganathan, S., Paiardini, A., Charman, S.A., Powell, A.K., Avery, V.M., McGowan, S., Scammells, P.J.
Eur.J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-05-21
Resolution2.100
CATH Insert Date17 Apr, 2016

PDB Images (37)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 18 Apr, 2016 Chopped
B 18 Apr, 2016 Chopped
C 18 Apr, 2016 Chopped
D 18 Apr, 2016 Chopped
E 18 Apr, 2016 Chopped
F 18 Apr, 2016 Chopped
G 18 Apr, 2016 Chopped
H 18 Apr, 2016 Chopped
I 18 Apr, 2016 Chopped
J 18 Apr, 2016 Chopped
K 18 Apr, 2016 Chopped
L 18 Apr, 2016 Chopped

CATH Domains (24)

Domain ID Date inserted into CATH Superfamily CATH Status
4zy2A01 03 May, 2016 3.40.220.10 Assigned
4zy2A02 03 May, 2016 3.40.630.10 Assigned
4zy2B01 03 May, 2016 3.40.220.10 Assigned
4zy2B02 03 May, 2016 3.40.630.10 Assigned
4zy2C01 03 May, 2016 3.40.220.10 Assigned
4zy2C02 03 May, 2016 3.40.630.10 Assigned
4zy2D01 03 May, 2016 3.40.220.10 Assigned
4zy2D02 03 May, 2016 3.40.630.10 Assigned
4zy2E01 03 May, 2016 3.40.220.10 Assigned
4zy2E02 03 May, 2016 3.40.630.10 Assigned
4zy2F01 03 May, 2016 3.40.220.10 Assigned
4zy2F02 03 May, 2016 3.40.630.10 Assigned
4zy2G01 03 May, 2016 3.40.220.10 Assigned
4zy2G02 03 May, 2016 3.40.630.10 Assigned
4zy2H01 03 May, 2016 3.40.220.10 Assigned
4zy2H02 03 May, 2016 3.40.630.10 Assigned
4zy2I01 03 May, 2016 3.40.220.10 Assigned
4zy2I02 03 May, 2016 3.40.630.10 Assigned
4zy2J01 03 May, 2016 3.40.220.10 Assigned
4zy2J02 03 May, 2016 3.40.630.10 Assigned
4zy2K01 03 May, 2016 3.40.220.10 Assigned
4zy2K02 03 May, 2016 3.40.630.10 Assigned
4zy2L01 03 May, 2016 3.40.220.10 Assigned
4zy2L02 03 May, 2016 3.40.630.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
A0A0L7M119 A0A0L7M119_PLAF4 Plasmodium falciparum Dd2 Uncharacterized protein
A0A0L7M119 A0A0L7M119_PLAF4 Plasmodium falciparum Dd2 Uncharacterized protein
A0A0L7M119 A0A0L7M119_PLAF4 Plasmodium falciparum Dd2 Uncharacterized protein
A0A0L7M119 A0A0L7M119_PLAF4 Plasmodium falciparum Dd2 Uncharacterized protein
A0A0L7M119 A0A0L7M119_PLAF4 Plasmodium falciparum Dd2 Uncharacterized protein
A0A0L7M119 A0A0L7M119_PLAF4 Plasmodium falciparum Dd2 Uncharacterized protein
A0A0L7M119 A0A0L7M119_PLAF4 Plasmodium falciparum Dd2 Uncharacterized protein
A0A0L7M119 A0A0L7M119_PLAF4 Plasmodium falciparum Dd2 Uncharacterized protein
A0A0L7M119 A0A0L7M119_PLAF4 Plasmodium falciparum Dd2 Uncharacterized protein
A0A0L7M119 A0A0L7M119_PLAF4 Plasmodium falciparum Dd2 Uncharacterized protein
A0A0L7M119 A0A0L7M119_PLAF4 Plasmodium falciparum Dd2 Uncharacterized protein
A0A0L7M119 A0A0L7M119_PLAF4 Plasmodium falciparum Dd2 Uncharacterized protein