PDB 4zx9

PDB Information

PDB4ZX9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum FcB1/Columbia
Primary Citation
Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.
Drinkwater, N., Vinh, N.B., Mistry, S.N., Bamert, R.S., Ruggeri, C., Holleran, J.P., Loganathan, S., Paiardini, A., Charman, S.A., Powell, A.K., Avery, V.M., McGowan, S., Scammells, P.J.
Eur.J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-05-20
Resolution2.600
CATH Insert Date10 Apr, 2016

PDB Images (37)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped
C 11 Apr, 2016 Chopped
D 11 Apr, 2016 Chopped
E 11 Apr, 2016 Chopped
F 11 Apr, 2016 Chopped
G 11 Apr, 2016 Chopped
H 11 Apr, 2016 Chopped
I 11 Apr, 2016 Chopped
J 11 Apr, 2016 Chopped
K 11 Apr, 2016 Chopped
L 11 Apr, 2016 Chopped

CATH Domains (24)

Domain ID Date inserted into CATH Superfamily CATH Status
4zx9A01 03 May, 2016 3.40.220.10 Assigned
4zx9A02 03 May, 2016 3.40.630.10 Assigned
4zx9B01 03 May, 2016 3.40.220.10 Assigned
4zx9B02 03 May, 2016 3.40.630.10 Assigned
4zx9C01 03 May, 2016 3.40.220.10 Assigned
4zx9C02 03 May, 2016 3.40.630.10 Assigned
4zx9D01 03 May, 2016 3.40.220.10 Assigned
4zx9D02 03 May, 2016 3.40.630.10 Assigned
4zx9E01 03 May, 2016 3.40.220.10 Assigned
4zx9E02 03 May, 2016 3.40.630.10 Assigned
4zx9F01 03 May, 2016 3.40.220.10 Assigned
4zx9F02 03 May, 2016 3.40.630.10 Assigned
4zx9G01 03 May, 2016 3.40.220.10 Assigned
4zx9G02 03 May, 2016 3.40.630.10 Assigned
4zx9H01 03 May, 2016 3.40.220.10 Assigned
4zx9H02 03 May, 2016 3.40.630.10 Assigned
4zx9I01 03 May, 2016 3.40.220.10 Assigned
4zx9I02 03 May, 2016 3.40.630.10 Assigned
4zx9J01 03 May, 2016 3.40.220.10 Assigned
4zx9J02 03 May, 2016 3.40.630.10 Assigned
4zx9K01 03 May, 2016 3.40.220.10 Assigned
4zx9K02 03 May, 2016 3.40.630.10 Assigned
4zx9L01 03 May, 2016 3.40.220.10 Assigned
4zx9L02 03 May, 2016 3.40.630.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein
A0A024V0B1 A0A024V0B1_PLAFA Plasmodium falciparum Vietnam Oak-Knoll (FVO) Uncharacterized protein