PDB 4zvv

PDB Information

PDB4ZVV
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition.
Boudreau, A., Purkey, H.E., Hitz, A., Robarge, K., Peterson, D., Labadie, S., Kwong, M., Hong, R., Gao, M., Del Nagro, C., Pusapati, R., Ma, S., Salphati, L., Pang, J., Zhou, A., Lai, T., Li, Y., Chen, Z., Wei, B., Yen, I., Sideris, S., McCleland, M., Firestein, R., Corson, L., Vanderbilt, A., Williams, S., Daemen, A., Belvin, M., Eigenbrot, C., Jackson, P.K., Malek, S., Hatzivassiliou, G., Sampath, D., Evangelista, M., O'Brien, T.
Nat.Chem.Biol.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2015-05-18
Resolution2.200
CATH Insert Date29 May, 2016

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 30 May, 2016 Chopped
B 30 May, 2016 Chopped
C 30 May, 2016 Chopped
D 30 May, 2016 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4zvvA01 11 Jul, 2016 3.40.50.720 Assigned
4zvvA02 11 Jul, 2016 3.90.110.10 Assigned
4zvvB01 11 Jul, 2016 3.40.50.720 Assigned
4zvvB02 11 Jul, 2016 3.90.110.10 Assigned
4zvvC01 11 Jul, 2016 3.40.50.720 Assigned
4zvvC02 11 Jul, 2016 3.90.110.10 Assigned
4zvvD01 11 Jul, 2016 3.40.50.720 Assigned
4zvvD02 11 Jul, 2016 3.90.110.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain