PDB 4zim

PDB Information

PDB4ZIM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
9H-Carbazole-1-carboxamides as potent and selective JAK2 inhibitors.
Zimmermann, K., Sang, X., Mastalerz, H.A., Johnson, W.L., Zhang, G., Liu, Q., Batt, D., Lombardo, L.J., Vyas, D., Trainor, G.L., Tokarski, J.S., Lorenzi, M.V., You, D., Gottardis, M.M., Lippy, J., Khan, J., Sack, J.S., Purandare, A.V.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2015-04-28
Resolution2.650
CATH Insert Date28 Jun, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4zimA01 27 Jul, 2015 3.30.200.20 Assigned
4zimA02 27 Jul, 2015 1.10.510.10 Assigned
4zimB01 27 Jul, 2015 3.30.200.20 Assigned
4zimB02 27 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O60674 JAK2_HUMAN Homo sapiens Tyrosine-protein kinase JAK2
O60674 JAK2_HUMAN Homo sapiens Tyrosine-protein kinase JAK2