PDB Information

PDB4YZD
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1 alpha Endoribonuclease Activity.
Concha, N.O., Smallwood, A., Bonnette, W., Totoritis, R., Zhang, G., Federowicz, K., Yang, J., Qi, H., Chen, S., Campobasso, N., Choudhry, A.E., Shuster, L.E., Evans, K.A., Ralph, J., Sweitzer, S., Heerding, D.A., Buser, C.A., Su, D.S., DeYoung, M.P.
Mol.Pharmacol.
HeaderTransferase
Released2015-03-24
Resolution3.100
CATH Insert Date29 Nov, 2015

PDB Images (13)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 30 Nov, 2015 Chopped
B 30 Nov, 2015 Chopped
C 30 Nov, 2015 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
4yzdA01 03 Dec, 2015 3.30.200.20 Assigned
4yzdA02 03 Dec, 2015 1.10.510.10 Assigned
4yzdA03 03 Dec, 2015 1.20.1440.180 Assigned
4yzdB01 03 Dec, 2015 3.30.200.20 Assigned
4yzdB02 03 Dec, 2015 1.10.510.10 Assigned
4yzdB03 03 Dec, 2015 1.20.1440.180 Assigned
4yzdC01 03 Dec, 2015 3.30.200.20 Assigned
4yzdC02 03 Dec, 2015 1.10.510.10 Assigned
4yzdC03 03 Dec, 2015 1.20.1440.180 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
O75460 ERN1_HUMAN Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1
O75460 ERN1_HUMAN Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1
O75460 ERN1_HUMAN Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1