PDB Information

PDB4YU2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Crystal structure of DYRK1A with harmine-derivatized AnnH-75 inhibitor
Chaikuad, A., Wurzlbauer, A., Nowak, R., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Bracher, F., Knapp, S., Structural Genomics Consortium (SGC)
To Be Published
HeaderTransferase
Released2015-03-18
Resolution2.900
CATH Insert Date28 Jun, 2015

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4yu2A01 22 Jul, 2015 3.30.200.20 Assigned
4yu2A02 22 Jul, 2015 1.10.510.10 Assigned
4yu2B01 22 Jul, 2015 3.30.200.20 Assigned
4yu2B02 22 Jul, 2015 1.10.510.10 Assigned
4yu2C01 22 Jul, 2015 3.30.200.20 Assigned
4yu2C02 22 Jul, 2015 1.10.510.10 Assigned
4yu2D01 22 Jul, 2015 3.30.200.20 Assigned
4yu2D02 22 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A