PDB 4ymj

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Overview

PDB Information

PDB	4YMJ
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors. Choi, H.S., Rucker, P.V., Wang, Z., Fan, Y., Albaugh, P., Chopiuk, G., Gessier, F., Sun, F., Adrian, F., Liu, G., Hood, T., Li, N., Jia, Y., Che, J., McCormack, S., Li, A., Li, J., Steffy, A., Culazzo, A., Tompkins, C., Phung, V., Kreusch, A., Lu, M., Hu, B., Chaudhary, A., Prashad, M., Tuntland, T., Liu, B., Harris, J., Seidel, H.M., Loren, J., Molteni, V. Acs Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2015-03-06
Resolution	2.000
CATH Insert Date	28 Jun, 2015

PDB Images (7)

Image of CATH 4ymj

4ymj

PDB 4ymj

Image of CATH 4ymjA

4ymjA

PDB Chain 4ymjA

Image of CATH 4ymjB

4ymjB

PDB Chain 4ymjB

Image of CATH 4ymjA01

4ymjA01

CATH Domain 4ymjA01

Image of CATH 4ymjA02

4ymjA02

CATH Domain 4ymjA02

Image of CATH 4ymjB01

4ymjB01

CATH Domain 4ymjB01

Image of CATH 4ymjB02

4ymjB02

CATH Domain 4ymjB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4ymjA01	22 Jul, 2015	3.30.200.20	Assigned
4ymjA02	22 Jul, 2015	1.10.510.10	Assigned
4ymjB01	22 Jul, 2015	3.30.200.20	Assigned
4ymjB02	22 Jul, 2015	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q16288	NTRK3_HUMAN	Homo sapiens	NT-3 growth factor receptor
Q16288	NTRK3_HUMAN	Homo sapiens	NT-3 growth factor receptor