PDB 4ymj

PDB Information

PDB4YMJ
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.
Choi, H.S., Rucker, P.V., Wang, Z., Fan, Y., Albaugh, P., Chopiuk, G., Gessier, F., Sun, F., Adrian, F., Liu, G., Hood, T., Li, N., Jia, Y., Che, J., McCormack, S., Li, A., Li, J., Steffy, A., Culazzo, A., Tompkins, C., Phung, V., Kreusch, A., Lu, M., Hu, B., Chaudhary, A., Prashad, M., Tuntland, T., Liu, B., Harris, J., Seidel, H.M., Loren, J., Molteni, V.
Acs Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2015-03-06
Resolution2.000
CATH Insert Date28 Jun, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4ymjA01 22 Jul, 2015 3.30.200.20 Assigned
4ymjA02 22 Jul, 2015 1.10.510.10 Assigned
4ymjB01 22 Jul, 2015 3.30.200.20 Assigned
4ymjB02 22 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q16288 NTRK3_HUMAN Homo sapiens NT-3 growth factor receptor
Q16288 NTRK3_HUMAN Homo sapiens NT-3 growth factor receptor