PDB 4y73

PDB Information

PDB4Y73
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Discovery of 5-Amino-N-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Inhibitors of IRAK4.
Lim, J., Altman, M.D., Baker, J., Brubaker, J.D., Chen, H., Chen, Y., Fischmann, T., Gibeau, C., Kleinschek, M.A., Leccese, E., Lesburg, C., Maclean, J.K., Moy, L.Y., Mulrooney, E.F., Presland, J., Rakhilina, L., Smith, G.F., Steinhuebel, D., Yang, R.
Acs Med.Chem.Lett.
HeaderTransferase
Released2015-02-13
Resolution2.140
CATH Insert Date28 Jun, 2015

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4y73A01 22 Jul, 2015 3.30.200.20 Assigned
4y73A02 22 Jul, 2015 1.10.510.10 Assigned
4y73B01 22 Jul, 2015 3.30.200.20 Assigned
4y73B02 22 Jul, 2015 1.10.510.10 Assigned
4y73C01 22 Jul, 2015 3.30.200.20 Assigned
4y73C02 22 Jul, 2015 1.10.510.10 Assigned
4y73D01 22 Jul, 2015 3.30.200.20 Assigned
4y73D02 22 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4
Q9NWZ3 IRAK4_HUMAN Homo sapiens Interleukin-1 receptor-associated kinase 4