PDB Information

PDB4Y6S
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourcePlasmodium falciparum (isolate 3D7)
Primary Citation
Synthesis and Bioactivity of beta-Substituted Fosmidomycin Analogues Targeting 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase.
Chofor, R., Sooriyaarachchi, S., Risseeuw, M.D., Bergfors, T., Pouyez, J., Johny, C., Haymond, A., Everaert, A., Dowd, C.S., Maes, L., Coenye, T., Alex, A., Couch, R.D., Jones, T.A., Wouters, J., Mowbray, S.L., Van Calenbergh, S.
J.Med.Chem.
HeaderOxidoreductase
Released2015-02-13
Resolution2.100
CATH Insert Date28 Jun, 2015

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4y6sA01 22 Jul, 2015 3.40.50.720 Assigned
4y6sA02 22 Jul, 2015 Holding pen
4y6sA03 22 Jul, 2015 1.10.1740.10 Assigned
4y6sB01 22 Jul, 2015 3.40.50.720 Assigned
4y6sB02 22 Jul, 2015 Holding pen
4y6sB03 22 Jul, 2015 1.10.1740.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8IKG4 DXR_PLAF7 Plasmodium falciparum 3D7 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic
Q8IKG4 DXR_PLAF7 Plasmodium falciparum 3D7 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic
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