PDB 4xy2

PDB Links
Overview

PDB Information

PDB	4XY2
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Addressing phototoxicity observed in a novel series of biaryl derivatives: Discovery of potent, selective and orally active phosphodiesterase 10A inhibitor ASP9436 Hamaguchi, W., Masuda, N., Miyamoto, S., Kikuchi, S., Narazaki, F., Shiina, Y., Seo, R., Amano, Y., Mihara, T., Moriguchi, H., Hattori, K. Bioorg.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-02-02
Resolution	2.030
CATH Insert Date	28 Jun, 2015

PDB Images (5)

Image of CATH 4xy2

4xy2

PDB 4xy2

Image of CATH 4xy2A

4xy2A

PDB Chain 4xy2A

Image of CATH 4xy2B

4xy2B

PDB Chain 4xy2B

Image of CATH 4xy2A00

4xy2A00

CATH Domain 4xy2A00

Image of CATH 4xy2B00

4xy2B00

CATH Domain 4xy2B00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4xy2A00	20 Jul, 2015	1.10.1300.10	Assigned
4xy2B00	22 Jul, 2015	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A