PDB Information

PDB4XWY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli bl21(de3)
Gene SourceHomo sapiens
Primary Citation
Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway.
Latremoliere, A., Latini, A., Andrews, N., Cronin, S.J., Fujita, M., Gorska, K., Hovius, R., Romero, C., Chuaiphichai, S., Painter, M., Miracca, G., Babaniyi, O., Remor, A.P., Duong, K., Riva, P., Barrett, L.B., Ferreiros, N., Naylor, A., Penninger, J.M., Tegeder, I., Zhong, J., Blagg, J., Channon, K.M., Johnsson, K., Costigan, M., Woolf, C.J.
Neuron
HeaderOxidoreductase
Released2015-01-29
Resolution2.350
CATH Insert Date16 Aug, 2015

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 17 Aug, 2015 Chopped
B 17 Aug, 2015 Chopped
C 17 Aug, 2015 Chopped
D 17 Aug, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4xwyA00 24 Aug, 2015 3.40.50.720 Assigned
4xwyB00 24 Aug, 2015 3.40.50.720 Assigned
4xwyC00 24 Aug, 2015 3.40.50.720 Assigned
4xwyD00 24 Aug, 2015 3.40.50.720 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P35270 SPRE_HUMAN Homo sapiens Sepiapterin reductase
P35270 SPRE_HUMAN Homo sapiens Sepiapterin reductase
P35270 SPRE_HUMAN Homo sapiens Sepiapterin reductase
P35270 SPRE_HUMAN Homo sapiens Sepiapterin reductase