PDB 4xv9

PDB Information

PDB4XV9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
RAF inhibitors that evade paradoxical MAPK pathway activation.
Zhang, C., Spevak, W., Zhang, Y., Burton, E.A., Ma, Y., Habets, G., Zhang, J., Lin, J., Ewing, T., Matusow, B., Tsang, G., Marimuthu, A., Cho, H., Wu, G., Wang, W., Fong, D., Nguyen, H., Shi, S., Womack, P., Nespi, M., Shellooe, R., Carias, H., Powell, B., Light, E., Sanftner, L., Walters, J., Tsai, J., West, B.L., Visor, G., Rezaei, H., Lin, P.S., Nolop, K., Ibrahim, P.N., Hirth, P., Bollag, G.
Nature
HeaderTransferase/Transferase Inhibitor
Released2015-01-26
Resolution2.000
CATH Insert Date08 Nov, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 09 Nov, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4xv9A01 12 Nov, 2015 3.30.200.20 Assigned
4xv9A02 12 Nov, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P15056 BRAF_HUMAN Homo sapiens Serine/threonine-protein kinase B-raf