PDB 4xu2

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Overview

PDB Information

PDB	4XU2
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Mycobacterium tuberculosis
Primary Citation	Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors. Bockman, M.R., Kalinda, A.S., Petrelli, R., De la Mora-Rey, T., Tiwari, D., Liu, F., Dawadi, S., Nandakumar, M., Rhee, K.Y., Schnappinger, D., Finzel, B.C., Aldrich, C.C. J.Med.Chem.
Header	Ligase/Ligase Inhibitor
Released	2015-01-24
Resolution	1.850
CATH Insert Date	20 Sep, 2015

PDB Images (7)

Image of CATH 4xu2

4xu2

PDB 4xu2

Image of CATH 4xu2A

4xu2A

PDB Chain 4xu2A

Image of CATH 4xu2B

4xu2B

PDB Chain 4xu2B

Image of CATH 4xu2A01

4xu2A01

CATH Domain 4xu2A01

Image of CATH 4xu2A02

4xu2A02

CATH Domain 4xu2A02

Image of CATH 4xu2B01

4xu2B01

CATH Domain 4xu2B01

Image of CATH 4xu2B02

4xu2B02

CATH Domain 4xu2B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	21 Sep, 2015	Chopped
B	21 Sep, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4xu2A01	30 Sep, 2015	3.30.930.10	Assigned
4xu2A02	30 Sep, 2015	2.30.30.100	Assigned
4xu2B01	30 Sep, 2015	3.30.930.10	Assigned
4xu2B02	30 Sep, 2015	2.30.30.100	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
I6YFP0	I6YFP0_MYCTU	Mycobacterium tuberculosis H37Rv	Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase)
I6YFP0	I6YFP0_MYCTU	Mycobacterium tuberculosis H37Rv	Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase)