PDB 4xsz

PDB Information

PDB4XSZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEscherichia coli (strain K12)
Primary Citation
CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition.
Bae, B., Nayak, D., Ray, A., Mustaev, A., Landick, R., Darst, S.A.
Proc.Natl.Acad.Sci.USA
HeaderTranscription/Antibiotic
Released2015-01-22
Resolution3.680
CATH Insert Date16 Aug, 2015

PDB Images (29)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 17 Aug, 2015 Chopped
B 17 Aug, 2015 Chopped
C 17 Aug, 2015 Holding pen
D 17 Aug, 2015 Holding pen
E 17 Aug, 2015 Chopped
F 17 Aug, 2015 Chopped
G 17 Aug, 2015 Chopped
H 17 Aug, 2015 Chopped
I 17 Aug, 2015 Holding pen
J 17 Aug, 2015 Holding pen
K 17 Aug, 2015 Chopped
L 17 Aug, 2015 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
4xszA01 21 Jul, 2016 3.30.1360.10 Assigned
4xszA02 21 Jul, 2016 2.170.120.12 Assigned
4xszB01 21 Jul, 2016 3.30.1360.10 Assigned
4xszB02 21 Jul, 2016 2.170.120.12 Assigned
4xszE00 24 Aug, 2015 3.90.940.10 Assigned
4xszF01 24 Aug, 2015 1.10.601.10 Assigned
4xszF02 24 Aug, 2015 1.10.10.10 Assigned
4xszF03 24 Aug, 2015 1.10.10.10 Assigned
4xszG01 21 Jul, 2016 3.30.1360.10 Assigned
4xszG02 21 Jul, 2016 2.170.120.12 Assigned
4xszH01 21 Jul, 2016 3.30.1360.10 Assigned
4xszH02 21 Jul, 2016 2.170.120.12 Assigned
4xszK00 24 Aug, 2015 3.90.940.10 Assigned
4xszL01 24 Aug, 2015 1.10.601.10 Assigned
4xszL02 24 Aug, 2015 1.10.10.10 Assigned
4xszL03 24 Aug, 2015 1.10.10.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
A7ZSI4 RPOA_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit alpha
B1IYV1 RPOZ_ECOLC Escherichia coli ATCC 8739 DNA-directed RNA polymerase subunit omega
A7ZUK1 RPOB_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit beta
A7ZSI4 RPOA_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit alpha
A7ZUK1 RPOB_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit beta
P00579 RPOD_ECOLI Escherichia coli K-12 RNA polymerase sigma factor RpoD
A7ZSI4 RPOA_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit alpha
A7ZUK2 RPOC_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit beta'
A7ZSI4 RPOA_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit alpha
P00579 RPOD_ECOLI Escherichia coli K-12 RNA polymerase sigma factor RpoD
A7ZUK2 RPOC_ECO24 Escherichia coli O139:H28 str. E24377A DNA-directed RNA polymerase subunit beta'
B1IYV1 RPOZ_ECOLC Escherichia coli ATCC 8739 DNA-directed RNA polymerase subunit omega
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