PDB 4x7o

PDB Information

PDB4X7O
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of 1H-Pyrazol-3(2H)-ones as Potent and Selective Inhibitors of Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK).
Smith, A.L., Andrews, K.L., Beckmann, H., Bellon, S.F., Beltran, P.J., Booker, S., Chen, H., Chung, Y.A., D'Angelo, N.D., Dao, J., Dellamaggiore, K.R., Jaeckel, P., Kendall, R., Labitzke, K., Long, A.M., Materna-Reichelt, S., Mitchell, P., Norman, M.H., Powers, D., Rose, M., Shaffer, P.L., Wu, M.M., Lipford, J.R.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-12-09
Resolution2.650
CATH Insert Date28 Jun, 2015

PDB Images (2)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Holding pen

CATH Domains (0)

Domain ID Date inserted into CATH Superfamily CATH Status

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9NZJ5 E2AK3_HUMAN Homo sapiens Eukaryotic translation initiation factor 2-alpha kinase 3