PDB Information

PDB4X6S
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
Watson, G.M., Gunzburg, M.J., Ambaye, N.D., Lucas, W.A., Traore, D.A., Kulkarni, K., Cergol, K.M., Payne, R.J., Panjikar, S., Pero, S.C., Perlmutter, P., Wilce, M.C., Wilce, J.A.
J.Med.Chem.
HeaderSignaling Protein/Inhibitor
Released2014-12-09
Resolution2.550
CATH Insert Date04 Oct, 2015

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Oct, 2015 Chopped
B 05 Oct, 2015 Chopped
L 05 Oct, 2015 Rejected
M 05 Oct, 2015 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4x6sA00 01 Nov, 2015 3.30.505.10 Assigned
4x6sB00 01 Nov, 2015 3.30.505.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7
Q14451 GRB7_HUMAN Homo sapiens Growth factor receptor-bound protein 7