PDB 4x6p

PDB Information

PDB4X6P
MethodX-RAY DIFFRACTION
Host OrganismKomagataella pastoris
Gene SourceHomo sapiens
Primary Citation
Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties.
Pinto, D.J., Smallheer, J.M., Corte, J.R., Austin, E.J., Wang, C., Fang, T., Smith, L.M., Rossi, K.A., Rendina, A.R., Bozarth, J.M., Zhang, G., Wei, A., Ramamurthy, V., Sheriff, S., Myers, J.E., Morin, P.E., Luettgen, J.M., Seiffert, D.A., Quan, M.L., Wexler, R.R.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-12-08
Resolution1.930
CATH Insert Date28 Jun, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4x6pA01 22 Jul, 2015 2.40.10.10 Assigned
4x6pA02 22 Jul, 2015 2.40.10.10 Assigned
4x6pB01 22 Jul, 2015 2.40.10.10 Assigned
4x6pB02 22 Jul, 2015 2.40.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03951 FA11_HUMAN Homo sapiens Coagulation factor XI
P03951 FA11_HUMAN Homo sapiens Coagulation factor XI