PDB 4wyo

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Overview

PDB Information

PDB	4WYO
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Saccharomyces cerevisiae
Primary Citation	Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes. Griffith, D.A., Kung, D.W., Esler, W.P., Amor, P.A., Bagley, S.W., Beysen, C., Carvajal-Gonzalez, S., Doran, S.D., Limberakis, C., Mathiowetz, A.M., McPherson, K., Price, D.A., Ravussin, E., Sonnenberg, G.E., Southers, J.A., Sweet, L.J., Turner, S.M., Vajdos, F.F. J.Med.Chem.
Header	Ligase/Ligase Inhibitor
Released	2014-11-17
Resolution	2.890
CATH Insert Date	28 Jun, 2015

PDB Images (9)

Image of CATH 4wyo

4wyo

PDB 4wyo

Image of CATH 4wyoB

4wyoB

PDB Chain 4wyoB

Image of CATH 4wyoC

4wyoC

PDB Chain 4wyoC

Image of CATH 4wyoB01

4wyoB01

CATH Domain 4wyoB01

Image of CATH 4wyoB02

4wyoB02

CATH Domain 4wyoB02

Image of CATH 4wyoB03

4wyoB03

CATH Domain 4wyoB03

Image of CATH 4wyoC01

4wyoC01

CATH Domain 4wyoC01

Image of CATH 4wyoC02

4wyoC02

CATH Domain 4wyoC02

Image of CATH 4wyoC03

4wyoC03

CATH Domain 4wyoC03

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
B	29 Jun, 2015	Chopped
C	29 Jun, 2015	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4wyoB01	20 Dec, 2016	3.90.226.10	Assigned
4wyoB02	20 Dec, 2016	2.40.460.10	Assigned
4wyoB03	20 Dec, 2016	3.90.226.10	Assigned
4wyoC01	20 Dec, 2016	3.90.226.10	Assigned
4wyoC02	20 Dec, 2016	2.40.460.10	Assigned
4wyoC03	20 Dec, 2016	3.90.226.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q00955	ACAC_YEAST	Saccharomyces cerevisiae S288C	Acetyl-CoA carboxylase
Q00955	ACAC_YEAST	Saccharomyces cerevisiae S288C	Acetyl-CoA carboxylase