PDB 4wwp

PDB Links
Overview

PDB Information

PDB	4WWP
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery and in Vivo Evaluation of (S)-N-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and Related PI3K delta Inhibitors for Inflammation and Autoimmune Disease. Cushing, T.D., Hao, X., Shin, Y., Andrews, K., Brown, M., Cardozo, M., Chen, Y., Duquette, J., Fisher, B., Gonzalez-Lopez de Turiso, F., He, X., Henne, K.R., Hu, Y.L., Hungate, R., Johnson, M.G., Kelly, R.C., Lucas, B., McCarter, J.D., McGee, L.R., Medina, J.C., San Miguel, T., Mohn, D., Pattaropong, V., Pettus, L.H., Reichelt, A., Rzasa, R.M., Seganish, J., Tasker, A.S., Wahl, R.C., Wannberg, S., Whittington, D.A., Whoriskey, J., Yu, G., Zalameda, L., Zhang, D., Metz, D.P. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2014-11-11
Resolution	2.400
CATH Insert Date	28 Dec, 2014

PDB Images (7)

Image of CATH 4wwp

4wwp

PDB 4wwp

Image of CATH 4wwpA

4wwpA

PDB Chain 4wwpA

Image of CATH 4wwpA01

4wwpA01

CATH Domain 4wwpA01

Image of CATH 4wwpA02

4wwpA02

CATH Domain 4wwpA02

Image of CATH 4wwpA03

4wwpA03

CATH Domain 4wwpA03

Image of CATH 4wwpA04

4wwpA04

CATH Domain 4wwpA04

Image of CATH 4wwpA05

4wwpA05

CATH Domain 4wwpA05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	29 Dec, 2014	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4wwpA01	06 Jan, 2015	3.10.20.90	Assigned
4wwpA02	06 Jan, 2015	2.60.40.150	Assigned
4wwpA03	06 Jan, 2015	1.25.40.70	Assigned
4wwpA04	06 Jan, 2015	3.30.1010.10	Assigned
4wwpA05	06 Jan, 2015	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform