PDB 4wwn

PDB Links
Overview

PDB Information

PDB	4WWN
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery and in Vivo Evaluation of (S)-N-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and Related PI3K delta Inhibitors for Inflammation and Autoimmune Disease. Cushing, T.D., Hao, X., Shin, Y., Andrews, K., Brown, M., Cardozo, M., Chen, Y., Duquette, J., Fisher, B., Gonzalez-Lopez de Turiso, F., He, X., Henne, K.R., Hu, Y.L., Hungate, R., Johnson, M.G., Kelly, R.C., Lucas, B., McCarter, J.D., McGee, L.R., Medina, J.C., San Miguel, T., Mohn, D., Pattaropong, V., Pettus, L.H., Reichelt, A., Rzasa, R.M., Seganish, J., Tasker, A.S., Wahl, R.C., Wannberg, S., Whittington, D.A., Whoriskey, J., Yu, G., Zalameda, L., Zhang, D., Metz, D.P. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2014-11-11
Resolution	2.700
CATH Insert Date	28 Dec, 2014

PDB Images (7)

Image of CATH 4wwn

4wwn

PDB 4wwn

Image of CATH 4wwnA

4wwnA

PDB Chain 4wwnA

Image of CATH 4wwnA01

4wwnA01

CATH Domain 4wwnA01

Image of CATH 4wwnA02

4wwnA02

CATH Domain 4wwnA02

Image of CATH 4wwnA03

4wwnA03

CATH Domain 4wwnA03

Image of CATH 4wwnA04

4wwnA04

CATH Domain 4wwnA04

Image of CATH 4wwnA05

4wwnA05

CATH Domain 4wwnA05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	29 Dec, 2014	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4wwnA01	06 Jan, 2015	3.10.20.90	Assigned
4wwnA02	06 Jan, 2015	2.60.40.150	Assigned
4wwnA03	06 Jan, 2015	1.25.40.70	Assigned
4wwnA04	06 Jan, 2015	3.30.1010.10	Assigned
4wwnA05	06 Jan, 2015	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform