PDB 4wv1

PDB Information

PDB4WV1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Redesigning a Monospecific Anti-FGFR3 Antibody to Add Selectivity for FGFR2 and Expand Antitumor Activity.
Yin, Y., Djakovic, S., Marsters, S., Tien, J., Peng, J., Tremayne, J., Lee, G., Neve, R.M., Wu, Y., Merchant, M., Ashkenazi, A., Carter, P.J.
Mol.Cancer Ther.
HeaderTransferase/Immune System
Released2014-11-04
Resolution2.360
CATH Insert Date27 Sep, 2015

PDB Images (17)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 28 Sep, 2015 Chopped
B 28 Sep, 2015 Chopped
C 28 Sep, 2015 Chopped
D 28 Sep, 2015 Chopped
E 28 Sep, 2015 Chopped
F 28 Sep, 2015 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
4wv1A01 05 Jul, 2016 2.60.40.10 Assigned
4wv1A02 05 Jul, 2016 2.60.40.10 Assigned
4wv1B01 30 Sep, 2015 2.60.40.10 Assigned
4wv1B02 30 Sep, 2015 2.60.40.10 Assigned
4wv1C00 30 Sep, 2015 2.60.40.10 Assigned
4wv1D01 05 Jul, 2016 2.60.40.10 Assigned
4wv1D02 05 Jul, 2016 2.60.40.10 Assigned
4wv1E01 01 Oct, 2015 2.60.40.10 Assigned
4wv1E02 01 Oct, 2015 2.60.40.10 Assigned
4wv1F00 01 Oct, 2015 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P21802 FGFR2_HUMAN Homo sapiens Fibroblast growth factor receptor 2
P21802 FGFR2_HUMAN Homo sapiens Fibroblast growth factor receptor 2