PDB 4wr8
PDB Information
| PDB | 4WR8 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Design, synthesis, and protein crystallography of biaryltriazoles as potent tautomerase inhibitors of macrophage migration inhibitory factor.
J.Am.Chem.Soc.
|
| Header | Isomerase/Isomerase Inhibitor |
| Released | 2014-10-23 |
| Resolution | 2.600 |
| CATH Insert Date | 28 Jun, 2015 |
PDB Images (37)
4wr8
PDB 4wr8
4wr8A
PDB Chain 4wr8A
4wr8B
PDB Chain 4wr8B
4wr8C
PDB Chain 4wr8C
4wr8D
PDB Chain 4wr8D
4wr8E
PDB Chain 4wr8E
4wr8F
PDB Chain 4wr8F
4wr8G
PDB Chain 4wr8G
4wr8H
PDB Chain 4wr8H
4wr8I
PDB Chain 4wr8I
4wr8J
PDB Chain 4wr8J
4wr8K
PDB Chain 4wr8K
4wr8L
PDB Chain 4wr8L
4wr8M
PDB Chain 4wr8M
4wr8N
PDB Chain 4wr8N
4wr8O
PDB Chain 4wr8O
4wr8P
PDB Chain 4wr8P
4wr8Q
PDB Chain 4wr8Q
4wr8R
PDB Chain 4wr8R
4wr8A00
CATH Domain 4wr8A00
4wr8B00
CATH Domain 4wr8B00
4wr8C00
CATH Domain 4wr8C00
4wr8D00
CATH Domain 4wr8D00
4wr8E00
CATH Domain 4wr8E00
4wr8F00
CATH Domain 4wr8F00
4wr8G00
CATH Domain 4wr8G00
4wr8H00
CATH Domain 4wr8H00
4wr8I00
CATH Domain 4wr8I00
4wr8J00
CATH Domain 4wr8J00
4wr8K00
CATH Domain 4wr8K00
4wr8L00
CATH Domain 4wr8L00
4wr8M00
CATH Domain 4wr8M00
4wr8N00
CATH Domain 4wr8N00
4wr8O00
CATH Domain 4wr8O00
4wr8P00
CATH Domain 4wr8P00
4wr8Q00
CATH Domain 4wr8Q00
4wr8R00
CATH Domain 4wr8R00
PDB Prints
PDB Chains (18)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 29 Jun, 2015 | Chopped |
| B | 29 Jun, 2015 | Chopped |
| C | 29 Jun, 2015 | Chopped |
| D | 29 Jun, 2015 | Chopped |
| E | 29 Jun, 2015 | Chopped |
| F | 29 Jun, 2015 | Chopped |
| G | 29 Jun, 2015 | Chopped |
| H | 29 Jun, 2015 | Chopped |
| I | 29 Jun, 2015 | Chopped |
| J | 29 Jun, 2015 | Chopped |
| K | 29 Jun, 2015 | Chopped |
| L | 29 Jun, 2015 | Chopped |
| M | 29 Jun, 2015 | Chopped |
| N | 29 Jun, 2015 | Chopped |
| O | 29 Jun, 2015 | Chopped |
| P | 29 Jun, 2015 | Chopped |
| Q | 29 Jun, 2015 | Chopped |
| R | 29 Jun, 2015 | Chopped |
CATH Domains (18)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4wr8A00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8B00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8C00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8D00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8E00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8F00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8G00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8H00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8I00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8J00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8K00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8L00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8M00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8N00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8O00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8P00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8Q00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
| 4wr8R00 | 22 Jul, 2015 | 3.30.429.10 | Assigned |
UniProtKB Entries (18)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |
| P14174 | MIF_HUMAN | Homo sapiens | Macrophage migration inhibitory factor |