PDB Information

PDB4WOV
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain.
Tokarski, J.S., Zupa-Fernandez, A., Tredup, J.A., Pike, K., Chang, C., Xie, D., Cheng, L., Pedicord, D., Muckelbauer, J., Johnson, S.R., Wu, S., Edavettal, S.C., Hong, Y., Witmer, M.R., Elkin, L.L., Blat, Y., Pitts, W.J., Weinstein, D.S., Burke, J.R.
J.Biol.Chem.
HeaderTransferase/Inhibitor
Released2014-10-16
Resolution1.800
CATH Insert Date28 Jun, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4wovA01 20 Jul, 2015 3.30.200.20 Assigned
4wovA02 20 Jul, 2015 1.10.510.10 Assigned
4wovB01 22 Jul, 2015 3.30.200.20 Assigned
4wovB02 22 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P29597 TYK2_HUMAN Homo sapiens Non-receptor tyrosine-protein kinase TYK2
P29597 TYK2_HUMAN Homo sapiens Non-receptor tyrosine-protein kinase TYK2