PDB 4wot

PDB Information

PDB4WOT
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Design, synthesis, and biological evaluation of novel, highly active soft ROCK inhibitors.
Boland, S., Bourin, A., Alen, J., Geraets, J., Schroeders, P., Castermans, K., Kindt, N., Boumans, N., Panitti, L., Fransen, S., Vanormelingen, J., Stassen, J.M., Leysen, D., Defert, O.
J. Med. Chem.
HeaderTransferase
Released2014-10-16
Resolution2.930
CATH Insert Date28 Jun, 2015

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4wotA01 07 Mar, 2018 3.30.200.20 Assigned
4wotA02 07 Mar, 2018 1.10.510.10 Assigned
4wotB01 07 Mar, 2018 3.30.200.20 Assigned
4wotB02 07 Mar, 2018 1.10.510.10 Assigned
4wotC01 07 Mar, 2018 3.30.200.20 Assigned
4wotC02 07 Mar, 2018 1.10.510.10 Assigned
4wotD01 07 Mar, 2018 3.30.200.20 Assigned
4wotD02 07 Mar, 2018 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2
O75116 ROCK2_HUMAN Homo sapiens Rho-associated protein kinase 2