PDB Information

PDB4W9N
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Crystal structure of the human Fatty Acid synthase enoyl-acyl carrier protein-reductase domain complexed with triclosan reveals allosteric protein-protein interface inhibition.
Sippel, K.H., Vyas, N.K., Zhang, W., Sankaran, B., Quiocho, F.A.
J.Biol.Chem.
HeaderOxidoreductase
Released2014-08-27
Resolution1.840
CATH Insert Date26 Oct, 2014

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 27 Oct, 2014 Chopped
B 27 Oct, 2014 Chopped
C 27 Oct, 2014 Chopped
D 27 Oct, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4w9nA01 02 Nov, 2014 3.90.180.10 Assigned
4w9nA02 02 Nov, 2014 3.40.50.720 Assigned
4w9nB01 02 Nov, 2014 3.90.180.10 Assigned
4w9nB02 02 Nov, 2014 3.40.50.720 Assigned
4w9nC01 02 Nov, 2014 3.90.180.10 Assigned
4w9nC02 02 Nov, 2014 3.40.50.720 Assigned
4w9nD01 02 Nov, 2014 3.90.180.10 Assigned
4w9nD02 02 Nov, 2014 3.40.50.720 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P49327 FAS_HUMAN Homo sapiens Fatty acid synthase
P49327 FAS_HUMAN Homo sapiens Fatty acid synthase
P49327 FAS_HUMAN Homo sapiens Fatty acid synthase
P49327 FAS_HUMAN Homo sapiens Fatty acid synthase