PDB Information

PDB4V0G
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Utilisation of Structure Based Design to Identify Novel, Irreversible Inhibitors of the Epidermal Growth Factor Receptor (Egfr) Harboring the Gatekeeper T790M Mutation
Hennessy, E.J., Chuaquini, C., Ashton, S., Coclough, N., Cross, D.A.E., Debreczeni, J.E., Eberlein, C., Gingipalli, L., Klinowska, T.C.M., Orme, J.P., Sha, L., Wu, X.
To be Published
HeaderTransferase
Released2014-09-16
Resolution3.000
CATH Insert Date10 Apr, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4v0gA01 29 Apr, 2016 3.30.200.20 Assigned
4v0gA02 29 Apr, 2016 1.10.510.10 Assigned
4v0gB01 29 Apr, 2016 3.30.200.20 Assigned
4v0gB02 29 Apr, 2016 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
CATH-Gene3D is a Global Biodata Core Resource Learn more...