PDB 4uvx
PDB Information
PDB | 4UVX |
Method | X-RAY DIFFRACTION |
Host Organism | ESCHERICHIA COLI BL21(DE3) |
Gene Source | HOMO SAPIENS |
Primary Citation | Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro.
Bioorg.Med.Chem.
|
Header | Transferase |
Released | 2014-08-08 |
Resolution | 1.950 |
CATH Insert Date | 16 Aug, 2015 |
PDB Images (5)
PDB Prints
PDB Chains (2)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 17 Aug, 2015 | Chopped |
B | 17 Aug, 2015 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4uvxA00 | 24 Aug, 2015 | 3.90.228.10 | Assigned |
4uvxB00 | 24 Aug, 2015 | 3.90.228.10 | Assigned |
UniProtKB Entries (2)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
Q9H2K2 | TNKS2_HUMAN | Homo sapiens | Poly [ADP-ribose] polymerase tankyrase-2 |
Q9H2K2 | TNKS2_HUMAN | Homo sapiens | Poly [ADP-ribose] polymerase tankyrase-2 |