PDB 4uvp

PDB Links
Overview

PDB Information

PDB	4UVP
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI BL21(DE3)
Gene Source	HOMO SAPIENS
Primary Citation	Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro. Paine, H.A., Nathubhai, A., Woon, E.C.Y., Sunderland, P.T., Wood, P.J., Mahon, M.F., Lloyd, M.D., Thompson, A.S., Haikarainen, T., Narwal, M., Lehtio, L., Threadgill, M.D. Bioorg.Med.Chem.
Header	Transferase
Released	2014-08-07
Resolution	1.750
CATH Insert Date	16 Aug, 2015

PDB Images (9)

Image of CATH 4uvp

4uvp

PDB 4uvp

Image of CATH 4uvpA

4uvpA

PDB Chain 4uvpA

Image of CATH 4uvpB

4uvpB

PDB Chain 4uvpB

Image of CATH 4uvpC

4uvpC

PDB Chain 4uvpC

Image of CATH 4uvpD

4uvpD

PDB Chain 4uvpD

Image of CATH 4uvpA00

4uvpA00

CATH Domain 4uvpA00

Image of CATH 4uvpB00

4uvpB00

CATH Domain 4uvpB00

Image of CATH 4uvpC00

4uvpC00

CATH Domain 4uvpC00

Image of CATH 4uvpD00

4uvpD00

CATH Domain 4uvpD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	17 Aug, 2015	Chopped
B	17 Aug, 2015	Chopped
C	17 Aug, 2015	Chopped
D	17 Aug, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4uvpA00	24 Aug, 2015	3.90.228.10	Assigned
4uvpB00	24 Aug, 2015	6.20.320.10	Assigned
4uvpC00	24 Aug, 2015	3.90.228.10	Assigned
4uvpD00	19 Aug, 2015	6.20.320.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2