PDB 4unn

PDB Information

PDB4UNN
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceMYCOBACTERIUM TUBERCULOSIS
Primary Citation
Structure Guided Lead Generation for M. Tuberculosis Thymidylate Kinase (Mtb Tmk): Discovery of 3-Cyanopyridone and 1,6-Naphthyridin-2-One as Potent Inhibitors.
Naik, M., Raichurkar, A., Bandodkar, B.S., Varun, B.V., Bhat, S., Kalkhambkar, R., Murugan, K., Menon, R., Bhat, J., Paul, B., Iyer, H., Hussein, S., Tucker, J.A., Vogtherr, M., Embrey, K.J., Mcmiken, H., Prasad, S., Gill, A., Ugarkar, B.G., Venkatraman, J., Read, J., Panda, M.
J.Med.Chem.
HeaderTransferase
Released2014-05-29
Resolution2.500
CATH Insert Date28 Jun, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4unnA00 15 Jul, 2015 3.40.50.300 Assigned
4unnB00 15 Jul, 2015 3.40.50.300 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P9WKE1 KTHY_MYCTU Mycobacterium tuberculosis H37Rv Thymidylate kinase
P9WKE1 KTHY_MYCTU Mycobacterium tuberculosis H37Rv Thymidylate kinase