PDB 4u2x

PDB Information

PDB4U2X
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceZaire ebolavirus
Primary Citation
Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1.
Xu, W., Edwards, M.R., Borek, D.M., Feagins, A.R., Mittal, A., Alinger, J.B., Berry, K.N., Yen, B., Hamilton, J., Brett, T.J., Pappu, R.V., Leung, D.W., Basler, C.F., Amarasinghe, G.K.
Cell Host Microbe
HeaderViral Protein
Released2014-07-18
Resolution3.150
CATH Insert Date24 Aug, 2014

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 25 Aug, 2014 Chopped
B 25 Aug, 2014 Chopped
C 25 Aug, 2014 Chopped
D 25 Aug, 2014 Chopped
E 25 Aug, 2014 Chopped
F 25 Aug, 2014 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4u2xA00 29 Aug, 2014 Holding pen
4u2xB00 29 Aug, 2014 Holding pen
4u2xC00 29 Aug, 2014 Holding pen
4u2xD00 27 Oct, 2014 1.25.10.10 Assigned
4u2xE00 27 Oct, 2014 1.25.10.10 Assigned
4u2xF00 27 Oct, 2014 1.25.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
O15131 IMA6_HUMAN Homo sapiens Importin subunit alpha-6
O15131 IMA6_HUMAN Homo sapiens Importin subunit alpha-6
O15131 IMA6_HUMAN Homo sapiens Importin subunit alpha-6