PDB Information

PDB4TVJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors.
Thorsell, A.G., Ekblad, T., Karlberg, T., Low, M., Pinto, A.F., Tresaugues, L., Moche, M., Cohen, M.S., Schuler, H.
J. Med. Chem.
HeaderTransferase
Released2014-06-27
Resolution2.100
CATH Insert Date16 Aug, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Aug, 2015 Chopped
B 17 Aug, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4tvjA01 19 Aug, 2015 1.20.142.10 Assigned
4tvjA02 19 Aug, 2015 3.90.228.10 Assigned
4tvjB01 24 Aug, 2015 1.20.142.10 Assigned
4tvjB02 24 Aug, 2015 3.90.228.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9UGN5 PARP2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 2
Q9UGN5 PARP2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 2