PDB 4rx2

PDB Information

PDB4RX2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEscherichia coli
Primary Citation
A Triple Mutant in the Omega-loop of TEM-1 beta-Lactamase Changes the Substrate Profile via a Large Conformational Change and an Altered General Base for Catalysis.
Stojanoski, V., Chow, D.C., Hu, L., Sankaran, B., Gilbert, H.F., Prasad, B.V., Palzkill, T.
J.Biol.Chem.
HeaderHydrolase
Released2014-12-08
Resolution2.320
CATH Insert Date28 Jun, 2015

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped
E 29 Jun, 2015 Chopped
F 29 Jun, 2015 Chopped
G 29 Jun, 2015 Chopped
H 29 Jun, 2015 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4rx2A00 10 Jul, 2015 3.40.710.10 Assigned
4rx2B00 11 Jul, 2015 3.40.710.10 Assigned
4rx2C00 10 Jul, 2015 3.40.710.10 Assigned
4rx2D00 10 Jul, 2015 3.40.710.10 Assigned
4rx2E00 10 Jul, 2015 3.40.710.10 Assigned
4rx2F00 10 Jul, 2015 3.40.710.10 Assigned
4rx2G00 11 Jul, 2015 3.40.710.10 Assigned
4rx2H00 11 Jul, 2015 3.40.710.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P62593 BLAT_ECOLX Escherichia coli Beta-lactamase TEM
P62593 BLAT_ECOLX Escherichia coli Beta-lactamase TEM
P62593 BLAT_ECOLX Escherichia coli Beta-lactamase TEM
P62593 BLAT_ECOLX Escherichia coli Beta-lactamase TEM
P62593 BLAT_ECOLX Escherichia coli Beta-lactamase TEM
P62593 BLAT_ECOLX Escherichia coli Beta-lactamase TEM
P62593 BLAT_ECOLX Escherichia coli Beta-lactamase TEM
P62593 BLAT_ECOLX Escherichia coli Beta-lactamase TEM