A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria.
Phillips, M.A., Lotharius, J., Marsh, K., White, J., Dayan, A., White, K.L., Njoroge, J.W., El Mazouni, F., Lao, Y., Kokkonda, S., Tomchick, D.R., Deng, X., Laird, T., Bhatia, S.N., March, S., Ng, C.L., Fidock, D.A., Wittlin, S., Lafuente-Monasterio, M., Benito, F.J., Alonso, L.M., Martinez, M.S., Jimenez-Diaz, M.B., Bazaga, S.F., Angulo-Barturen, I., Haselden, J.N., Louttit, J., Cui, Y., Sridhar, A., Zeeman, A.M., Kocken, C., Sauerwein, R., Dechering, K., Avery, V.M., Duffy, S., Delves, M., Sinden, R., Ruecker, A., Wickham, K.S., Rochford, R., Gahagen, J., Iyer, L., Riccio, E., Mirsalis, J., Bathhurst, I., Rueckle, T., Ding, X., Campo, B., Leroy, D., Rogers, M.J., Rathod, P.K., Burrows, J.N., Charman, S.A.
Sci Transl Med