PDB 4rwk
PDB Information
| PDB | 4RWK |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Illuminating the Molecular Mechanisms of Tyrosine Kinase Inhibitor Resistance for the FGFR1 Gatekeeper Mutation: The Achilles' Heel of Targeted Therapy.
Acs Chem.Biol.
|
| Header | Transferase/Transferase Inhibitor |
| Released | 2014-12-04 |
| Resolution | 2.980 |
| CATH Insert Date | 28 Jun, 2015 |
PDB Prints
PDB Chains (2)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 29 Jun, 2015 | Chopped |
| B | 29 Jun, 2015 | Chopped |
CATH Domains (4)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4rwkA01 | 10 Jul, 2015 | 3.30.200.20 | Assigned |
| 4rwkA02 | 10 Jul, 2015 | 1.10.510.10 | Assigned |
| 4rwkB01 | 10 Jul, 2015 | 3.30.200.20 | Assigned |
| 4rwkB02 | 10 Jul, 2015 | 1.10.510.10 | Assigned |
UniProtKB Entries (2)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P11362 | FGFR1_HUMAN | Homo sapiens | Fibroblast growth factor receptor 1 |
| P11362 | FGFR1_HUMAN | Homo sapiens | Fibroblast growth factor receptor 1 |