PDB Information

PDB4RVI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Enhanced antiviral activity by the P2-tris-tetrahydrofuran moiety of GRL-0519, a novel nonpeptidic HIV-1 protease inhibitor (PI), against multi-PI-resistant and highly darunavir-resistant strains of HIV-1
Yedidi, R.S., Maeda, K., Aoki, M., Garimella, H., Rao, K.V., Akasapu, S., Davis, D.A., Kaufman, J.D., Das, D., Wingfield, P.T., Amano, M., Ghosh, A.K., Mitsuya, H.
To be Published
HeaderHydrolase/Hydrolase Inhibitor
Released2014-11-26
Resolution1.990
CATH Insert Date15 May, 2016

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 May, 2016 Chopped
B 16 May, 2016 Chopped
C 16 May, 2016 Chopped
D 16 May, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4rviA00 10 Jul, 2016 2.40.70.10 Assigned
4rviB00 10 Jul, 2016 2.40.70.10 Assigned
4rviC00 10 Jul, 2016 2.40.70.10 Assigned
4rviD00 10 Jul, 2016 2.40.70.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9J006 Q9J006_9HIV1 Human immunodeficiency virus 1 Protease
Q9J006 Q9J006_9HIV1 Human immunodeficiency virus 1 Protease
Q9J006 Q9J006_9HIV1 Human immunodeficiency virus 1 Protease
Q9J006 Q9J006_9HIV1 Human immunodeficiency virus 1 Protease