PDB 4rad
PDB Information
| PDB | 4RAD |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group As Inhibitors of the Human, Plasmodium falciparum and vivax 6-Oxopurine Phosphoribosyltransferases and Their Prodrugs As Antimalarial Agents.
J.Med.Chem.
|
| Header | Transferase/Transferase Inhibitor |
| Released | 2014-09-10 |
| Resolution | 2.000 |
| CATH Insert Date | 28 Jun, 2015 |
PDB Images (17)
4rad
PDB 4rad
4radA
PDB Chain 4radA
4radB
PDB Chain 4radB
4radC
PDB Chain 4radC
4radD
PDB Chain 4radD
4radE
PDB Chain 4radE
4radF
PDB Chain 4radF
4radG
PDB Chain 4radG
4radH
PDB Chain 4radH
4radA00
CATH Domain 4radA00
4radB00
CATH Domain 4radB00
4radC00
CATH Domain 4radC00
4radD00
CATH Domain 4radD00
4radE00
CATH Domain 4radE00
4radF00
CATH Domain 4radF00
4radG00
CATH Domain 4radG00
4radH00
CATH Domain 4radH00
PDB Prints
PDB Chains (8)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 29 Jun, 2015 | Chopped |
| B | 29 Jun, 2015 | Chopped |
| C | 29 Jun, 2015 | Chopped |
| D | 29 Jun, 2015 | Chopped |
| E | 29 Jun, 2015 | Chopped |
| F | 29 Jun, 2015 | Chopped |
| G | 29 Jun, 2015 | Chopped |
| H | 29 Jun, 2015 | Chopped |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4radA00 | 10 Jul, 2015 | 3.40.50.2020 | Assigned |
| 4radB00 | 10 Jul, 2015 | 3.40.50.2020 | Assigned |
| 4radC00 | 10 Jul, 2015 | 3.40.50.2020 | Assigned |
| 4radD00 | 10 Jul, 2015 | 3.40.50.2020 | Assigned |
| 4radE00 | 10 Jul, 2015 | 3.40.50.2020 | Assigned |
| 4radF00 | 10 Jul, 2015 | 3.40.50.2020 | Assigned |
| 4radG00 | 10 Jul, 2015 | 3.40.50.2020 | Assigned |
| 4radH00 | 10 Jul, 2015 | 3.40.50.2020 | Assigned |
UniProtKB Entries (8)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P00492 | HPRT_HUMAN | Homo sapiens | Hypoxanthine-guanine phosphoribosyltransferase |
| P00492 | HPRT_HUMAN | Homo sapiens | Hypoxanthine-guanine phosphoribosyltransferase |
| P00492 | HPRT_HUMAN | Homo sapiens | Hypoxanthine-guanine phosphoribosyltransferase |
| P00492 | HPRT_HUMAN | Homo sapiens | Hypoxanthine-guanine phosphoribosyltransferase |
| P00492 | HPRT_HUMAN | Homo sapiens | Hypoxanthine-guanine phosphoribosyltransferase |
| P00492 | HPRT_HUMAN | Homo sapiens | Hypoxanthine-guanine phosphoribosyltransferase |
| P00492 | HPRT_HUMAN | Homo sapiens | Hypoxanthine-guanine phosphoribosyltransferase |
| P00492 | HPRT_HUMAN | Homo sapiens | Hypoxanthine-guanine phosphoribosyltransferase |