PDB 4r7m

PDB Information

PDB4R7M
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum 3D7
Primary Citation
Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors.
Mistry, S.N., Drinkwater, N., Ruggeri, C., Sivaraman, K.K., Loganathan, S., Fletcher, S., Drag, M., Paiardini, A., Avery, V.M., Scammells, P.J., McGowan, S.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-08-28
Resolution2.850
CATH Insert Date09 Nov, 2014

PDB Images (37)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 10 Nov, 2014 Chopped
B 10 Nov, 2014 Chopped
C 10 Nov, 2014 Chopped
D 10 Nov, 2014 Chopped
E 10 Nov, 2014 Chopped
F 10 Nov, 2014 Chopped
G 10 Nov, 2014 Chopped
H 10 Nov, 2014 Chopped
I 10 Nov, 2014 Chopped
J 10 Nov, 2014 Chopped
K 10 Nov, 2014 Chopped
L 10 Nov, 2014 Chopped

CATH Domains (24)

Domain ID Date inserted into CATH Superfamily CATH Status
4r7mA01 14 Nov, 2014 3.40.220.10 Assigned
4r7mA02 14 Nov, 2014 3.40.630.10 Assigned
4r7mB01 14 Nov, 2014 3.40.220.10 Assigned
4r7mB02 14 Nov, 2014 3.40.630.10 Assigned
4r7mC01 14 Nov, 2014 3.40.220.10 Assigned
4r7mC02 14 Nov, 2014 3.40.630.10 Assigned
4r7mD01 14 Nov, 2014 3.40.220.10 Assigned
4r7mD02 14 Nov, 2014 3.40.630.10 Assigned
4r7mE01 14 Nov, 2014 3.40.220.10 Assigned
4r7mE02 14 Nov, 2014 3.40.630.10 Assigned
4r7mF01 14 Nov, 2014 3.40.220.10 Assigned
4r7mF02 14 Nov, 2014 3.40.630.10 Assigned
4r7mG01 14 Nov, 2014 3.40.220.10 Assigned
4r7mG02 14 Nov, 2014 3.40.630.10 Assigned
4r7mH01 14 Nov, 2014 3.40.220.10 Assigned
4r7mH02 14 Nov, 2014 3.40.630.10 Assigned
4r7mI01 14 Nov, 2014 3.40.220.10 Assigned
4r7mI02 14 Nov, 2014 3.40.630.10 Assigned
4r7mJ01 14 Nov, 2014 3.40.220.10 Assigned
4r7mJ02 14 Nov, 2014 3.40.630.10 Assigned
4r7mK01 14 Nov, 2014 3.40.220.10 Assigned
4r7mK02 14 Nov, 2014 3.40.630.10 Assigned
4r7mL01 14 Nov, 2014 3.40.220.10 Assigned
4r7mL02 14 Nov, 2014 3.40.630.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase
Q8IL11 Q8IL11_PLAF7 Plasmodium falciparum 3D7 M17 leucyl aminopeptidase