PDB 4r5w

PDB Links
Overview

PDB Information

PDB	4R5W
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors. Thorsell, A.G., Ekblad, T., Karlberg, T., Low, M., Pinto, A.F., Tresaugues, L., Moche, M., Cohen, M.S., Schuler, H. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2014-08-22
Resolution	2.840
CATH Insert Date	20 Sep, 2015

PDB Images (7)

Image of CATH 4r5w

4r5w

PDB 4r5w

Image of CATH 4r5wA

4r5wA

PDB Chain 4r5wA

Image of CATH 4r5wB

4r5wB

PDB Chain 4r5wB

Image of CATH 4r5wA01

4r5wA01

CATH Domain 4r5wA01

Image of CATH 4r5wA02

4r5wA02

CATH Domain 4r5wA02

Image of CATH 4r5wB01

4r5wB01

CATH Domain 4r5wB01

Image of CATH 4r5wB02

4r5wB02

CATH Domain 4r5wB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	21 Sep, 2015	Chopped
B	21 Sep, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4r5wA01	30 Sep, 2015	1.20.142.10	Assigned
4r5wA02	30 Sep, 2015	3.90.228.10	Assigned
4r5wB01	30 Sep, 2015	1.20.142.10	Assigned
4r5wB02	30 Sep, 2015	3.90.228.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P09874	PARP1_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase 1
P09874	PARP1_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase 1