PDB 4r5s

PDB Information

PDB4R5S
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.
Tan, L., Wang, J., Tanizaki, J., Huang, Z., Aref, A.R., Rusan, M., Zhu, S.J., Zhang, Y., Ercan, D., Liao, R.G., Capelletti, M., Zhou, W., Hur, W., Kim, N., Sim, T., Gaudet, S., Barbie, D.A., Yeh, J.R., Yun, C.H., Hammerman, P.S., Mohammadi, M., Janne, P.A., Gray, N.S.
Proc.Natl.Acad.Sci.USA
HeaderTransferase
Released2014-08-22
Resolution3.000
CATH Insert Date30 Nov, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 01 Dec, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4r5sA01 02 Dec, 2014 3.30.200.20 Assigned
4r5sA02 02 Dec, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor