PDB 4qxm

PDB Information

PDB4QXM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceMycobacterium tuberculosis H37Rv
Primary Citation
N-Benzyl-4-((heteroaryl)methyl)benzamides: A New Class of Direct NADH-Dependent 2-trans Enoyl-Acyl Carrier Protein Reductase (InhA) Inhibitors with Antitubercular Activity.
Guardia, A., Gulten, G., Fernandez, R., Gomez, J., Wang, F., Convery, M., Blanco, D., Martinez, M., Perez-Herran, E., Alonso, M., Ortega, F., Rullas, J., Calvo, D., Mata, L., Young, R., Sacchettini, J.C., Mendoza-Losana, A., Remuinan, M., Ballell Pages, L., Castro-Pichel, J.
Chemmedchem
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2014-07-21
Resolution2.200
CATH Insert Date16 Aug, 2015

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 17 Aug, 2015 Chopped
C 17 Aug, 2015 Chopped
E 17 Aug, 2015 Chopped
G 17 Aug, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4qxmA00 24 Aug, 2015 3.40.50.720 Assigned
4qxmC00 19 Aug, 2015 3.40.50.720 Assigned
4qxmE00 24 Aug, 2015 3.40.50.720 Assigned
4qxmG00 24 Aug, 2015 3.40.50.720 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P9WGR1 INHA_MYCTU Mycobacterium tuberculosis H37Rv Enoyl-[acyl-carrier-protein] reductase [NADH]
P9WGR1 INHA_MYCTU Mycobacterium tuberculosis H37Rv Enoyl-[acyl-carrier-protein] reductase [NADH]
P9WGR1 INHA_MYCTU Mycobacterium tuberculosis H37Rv Enoyl-[acyl-carrier-protein] reductase [NADH]
P9WGR1 INHA_MYCTU Mycobacterium tuberculosis H37Rv Enoyl-[acyl-carrier-protein] reductase [NADH]