PDB 4qpa

PDB Information

PDB4QPA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors.
Burdick, D.J., Wang, S., Heise, C., Pan, B., Drummond, J., Yin, J., Goeser, L., Magnuson, S., Blaney, J., Moffat, J., Wang, W., Chen, H.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2014-06-22
Resolution2.850
CATH Insert Date04 Oct, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Oct, 2015 Chopped
B 05 Oct, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4qpaA01 01 Nov, 2015 3.30.200.20 Assigned
4qpaA02 01 Nov, 2015 1.10.510.10 Assigned
4qpaB01 31 Oct, 2015 3.30.200.20 Assigned
4qpaB02 31 Oct, 2015 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P28482 MK01_HUMAN Homo sapiens Mitogen-activated protein kinase 1
P28482 MK01_HUMAN Homo sapiens Mitogen-activated protein kinase 1