PDB Information

PDB4QP7
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Fragment-based discovery of potent ERK2 pyrrolopyrazine inhibitors.
Burdick, D.J., Wang, S., Heise, C., Pan, B., Drummond, J., Yin, J., Goeser, L., Magnuson, S., Blaney, J., Moffat, J., Wang, W., Chen, H.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2014-06-22
Resolution2.250
CATH Insert Date04 Oct, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Oct, 2015 Chopped
B 05 Oct, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4qp7A01 01 Nov, 2015 3.30.200.20 Assigned
4qp7A02 01 Nov, 2015 1.10.510.10 Assigned
4qp7B01 01 Nov, 2015 3.30.200.20 Assigned
4qp7B02 01 Nov, 2015 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P28482 MK01_HUMAN Homo sapiens Mitogen-activated protein kinase 1
P28482 MK01_HUMAN Homo sapiens Mitogen-activated protein kinase 1