PDB 4qlv

PDB Links
Overview

PDB Information

PDB	4QLV
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Structure-based design of beta 1i or beta 5i specific inhibitors of human immunoproteasomes De Bruin, G., Huber, E.M., Xin, B.T., Van Rooden, E.J., Al-Ayed, K., Kim, K.B., Kisselev, A.F., Driessen, C., Van der Stelt, M., Van der Marel, G.A., Groll, M., Overkleeft, H.S. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-06-13
Resolution	2.900
CATH Insert Date	10 Aug, 2014

PDB Images (57)

4qlv

PDB 4qlv

4qlva

PDB Chain 4qlva

4qlvA

PDB Chain 4qlvA

4qlvb

PDB Chain 4qlvb

4qlvB

PDB Chain 4qlvB

4qlvC

PDB Chain 4qlvC

4qlvD

PDB Chain 4qlvD

4qlvE

PDB Chain 4qlvE

4qlvF

PDB Chain 4qlvF

4qlvG

PDB Chain 4qlvG

4qlvH

PDB Chain 4qlvH

4qlvI

PDB Chain 4qlvI

4qlvJ

PDB Chain 4qlvJ

4qlvK

PDB Chain 4qlvK

4qlvL

PDB Chain 4qlvL

4qlvM

PDB Chain 4qlvM

4qlvN

PDB Chain 4qlvN

4qlvO

PDB Chain 4qlvO

4qlvP

PDB Chain 4qlvP

4qlvQ

PDB Chain 4qlvQ

4qlvR

PDB Chain 4qlvR

4qlvS

PDB Chain 4qlvS

4qlvT

PDB Chain 4qlvT

4qlvU

PDB Chain 4qlvU

4qlvV

PDB Chain 4qlvV

4qlvW

PDB Chain 4qlvW

4qlvX

PDB Chain 4qlvX

4qlvY

PDB Chain 4qlvY

4qlvZ

PDB Chain 4qlvZ

4qlva00

CATH Domain 4qlva00

4qlvA00

CATH Domain 4qlvA00

4qlvb00

CATH Domain 4qlvb00

4qlvB00

CATH Domain 4qlvB00

4qlvC00

CATH Domain 4qlvC00

4qlvD00

CATH Domain 4qlvD00

4qlvE00

CATH Domain 4qlvE00

4qlvF00

CATH Domain 4qlvF00

4qlvG00

CATH Domain 4qlvG00

4qlvH00

CATH Domain 4qlvH00

4qlvI00

CATH Domain 4qlvI00

4qlvJ00

CATH Domain 4qlvJ00

4qlvK00

CATH Domain 4qlvK00

4qlvL00

CATH Domain 4qlvL00

4qlvM00

CATH Domain 4qlvM00

4qlvN00

CATH Domain 4qlvN00

4qlvO00

CATH Domain 4qlvO00

4qlvP00

CATH Domain 4qlvP00

4qlvQ00

CATH Domain 4qlvQ00

4qlvR00

CATH Domain 4qlvR00

4qlvS00

CATH Domain 4qlvS00

4qlvT00

CATH Domain 4qlvT00

4qlvU00

CATH Domain 4qlvU00

4qlvV00

CATH Domain 4qlvV00

4qlvW00

CATH Domain 4qlvW00

4qlvX00

CATH Domain 4qlvX00

4qlvY00

CATH Domain 4qlvY00

4qlvZ00

CATH Domain 4qlvZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	11 Aug, 2014	Chopped
A	11 Aug, 2014	Chopped
b	11 Aug, 2014	Chopped
B	11 Aug, 2014	Chopped
C	11 Aug, 2014	Chopped
D	11 Aug, 2014	Chopped
E	11 Aug, 2014	Chopped
F	11 Aug, 2014	Chopped
G	11 Aug, 2014	Chopped
H	11 Aug, 2014	Chopped
I	11 Aug, 2014	Chopped
J	11 Aug, 2014	Chopped
K	11 Aug, 2014	Chopped
L	11 Aug, 2014	Chopped
M	11 Aug, 2014	Chopped
N	11 Aug, 2014	Chopped
O	11 Aug, 2014	Chopped
P	11 Aug, 2014	Chopped
Q	11 Aug, 2014	Chopped
R	11 Aug, 2014	Chopped
S	11 Aug, 2014	Chopped
T	11 Aug, 2014	Chopped
U	11 Aug, 2014	Chopped
V	11 Aug, 2014	Chopped
W	11 Aug, 2014	Chopped
X	11 Aug, 2014	Chopped
Y	11 Aug, 2014	Chopped
Z	11 Aug, 2014	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4qlva00	20 Aug, 2014	3.60.20.10	Assigned
4qlvA00	20 Aug, 2014	3.60.20.10	Assigned
4qlvb00	20 Aug, 2014	3.60.20.10	Assigned
4qlvB00	20 Aug, 2014	3.60.20.10	Assigned
4qlvC00	20 Aug, 2014	3.60.20.10	Assigned
4qlvD00	20 Aug, 2014	3.60.20.10	Assigned
4qlvE00	20 Aug, 2014	3.60.20.10	Assigned
4qlvF00	20 Aug, 2014	3.60.20.10	Assigned
4qlvG00	20 Aug, 2014	3.60.20.10	Assigned
4qlvH00	20 Aug, 2014	3.60.20.10	Assigned
4qlvI00	20 Aug, 2014	3.60.20.10	Assigned
4qlvJ00	20 Aug, 2014	3.60.20.10	Assigned
4qlvK00	20 Aug, 2014	3.60.20.10	Assigned
4qlvL00	20 Aug, 2014	3.60.20.10	Assigned
4qlvM00	20 Aug, 2014	3.60.20.10	Assigned
4qlvN00	20 Aug, 2014	3.60.20.10	Assigned
4qlvO00	20 Aug, 2014	3.60.20.10	Assigned
4qlvP00	20 Aug, 2014	3.60.20.10	Assigned
4qlvQ00	20 Aug, 2014	3.60.20.10	Assigned
4qlvR00	20 Aug, 2014	3.60.20.10	Assigned
4qlvS00	20 Aug, 2014	3.60.20.10	Assigned
4qlvT00	20 Aug, 2014	3.60.20.10	Assigned
4qlvU00	20 Aug, 2014	3.60.20.10	Assigned
4qlvV00	20 Aug, 2014	3.60.20.10	Assigned
4qlvW00	20 Aug, 2014	3.60.20.10	Assigned
4qlvX00	20 Aug, 2014	3.60.20.10	Assigned
4qlvY00	20 Aug, 2014	3.60.20.10	Assigned
4qlvZ00	20 Aug, 2014	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6