PDB 4qlq

PDB Links
Overview

PDB Information

PDB	4QLQ
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Structure-based design of beta 1i or beta 5i specific inhibitors of human immunoproteasomes De Bruin, G., Huber, E.M., Xin, B.T., Van Rooden, E.J., Al-Ayed, K., Kim, K.B., Kisselev, A.F., Driessen, C., Van der Stelt, M., Van der Marel, G.A., Groll, M., Overkleeft, H.S. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-06-13
Resolution	2.400
CATH Insert Date	10 Aug, 2014

PDB Images (57)

4qlq

PDB 4qlq

4qlqa

PDB Chain 4qlqa

4qlqA

PDB Chain 4qlqA

4qlqb

PDB Chain 4qlqb

4qlqB

PDB Chain 4qlqB

4qlqC

PDB Chain 4qlqC

4qlqD

PDB Chain 4qlqD

4qlqE

PDB Chain 4qlqE

4qlqF

PDB Chain 4qlqF

4qlqG

PDB Chain 4qlqG

4qlqH

PDB Chain 4qlqH

4qlqI

PDB Chain 4qlqI

4qlqJ

PDB Chain 4qlqJ

4qlqK

PDB Chain 4qlqK

4qlqL

PDB Chain 4qlqL

4qlqM

PDB Chain 4qlqM

4qlqN

PDB Chain 4qlqN

4qlqO

PDB Chain 4qlqO

4qlqP

PDB Chain 4qlqP

4qlqQ

PDB Chain 4qlqQ

4qlqR

PDB Chain 4qlqR

4qlqS

PDB Chain 4qlqS

4qlqT

PDB Chain 4qlqT

4qlqU

PDB Chain 4qlqU

4qlqV

PDB Chain 4qlqV

4qlqW

PDB Chain 4qlqW

4qlqX

PDB Chain 4qlqX

4qlqY

PDB Chain 4qlqY

4qlqZ

PDB Chain 4qlqZ

4qlqa00

CATH Domain 4qlqa00

4qlqA00

CATH Domain 4qlqA00

4qlqb00

CATH Domain 4qlqb00

4qlqB00

CATH Domain 4qlqB00

4qlqC00

CATH Domain 4qlqC00

4qlqD00

CATH Domain 4qlqD00

4qlqE00

CATH Domain 4qlqE00

4qlqF00

CATH Domain 4qlqF00

4qlqG00

CATH Domain 4qlqG00

4qlqH00

CATH Domain 4qlqH00

4qlqI00

CATH Domain 4qlqI00

4qlqJ00

CATH Domain 4qlqJ00

4qlqK00

CATH Domain 4qlqK00

4qlqL00

CATH Domain 4qlqL00

4qlqM00

CATH Domain 4qlqM00

4qlqN00

CATH Domain 4qlqN00

4qlqO00

CATH Domain 4qlqO00

4qlqP00

CATH Domain 4qlqP00

4qlqQ00

CATH Domain 4qlqQ00

4qlqR00

CATH Domain 4qlqR00

4qlqS00

CATH Domain 4qlqS00

4qlqT00

CATH Domain 4qlqT00

4qlqU00

CATH Domain 4qlqU00

4qlqV00

CATH Domain 4qlqV00

4qlqW00

CATH Domain 4qlqW00

4qlqX00

CATH Domain 4qlqX00

4qlqY00

CATH Domain 4qlqY00

4qlqZ00

CATH Domain 4qlqZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	11 Aug, 2014	Chopped
A	11 Aug, 2014	Chopped
b	11 Aug, 2014	Chopped
B	11 Aug, 2014	Chopped
C	11 Aug, 2014	Chopped
D	11 Aug, 2014	Chopped
E	11 Aug, 2014	Chopped
F	11 Aug, 2014	Chopped
G	11 Aug, 2014	Chopped
H	11 Aug, 2014	Chopped
I	11 Aug, 2014	Chopped
J	11 Aug, 2014	Chopped
K	11 Aug, 2014	Chopped
L	11 Aug, 2014	Chopped
M	11 Aug, 2014	Chopped
N	11 Aug, 2014	Chopped
O	11 Aug, 2014	Chopped
P	11 Aug, 2014	Chopped
Q	11 Aug, 2014	Chopped
R	11 Aug, 2014	Chopped
S	11 Aug, 2014	Chopped
T	11 Aug, 2014	Chopped
U	11 Aug, 2014	Chopped
V	11 Aug, 2014	Chopped
W	11 Aug, 2014	Chopped
X	11 Aug, 2014	Chopped
Y	11 Aug, 2014	Chopped
Z	11 Aug, 2014	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4qlqa00	20 Aug, 2014	3.60.20.10	Assigned
4qlqA00	20 Aug, 2014	3.60.20.10	Assigned
4qlqb00	20 Aug, 2014	3.60.20.10	Assigned
4qlqB00	20 Aug, 2014	3.60.20.10	Assigned
4qlqC00	20 Aug, 2014	3.60.20.10	Assigned
4qlqD00	20 Aug, 2014	3.60.20.10	Assigned
4qlqE00	20 Aug, 2014	3.60.20.10	Assigned
4qlqF00	20 Aug, 2014	3.60.20.10	Assigned
4qlqG00	20 Aug, 2014	3.60.20.10	Assigned
4qlqH00	20 Aug, 2014	3.60.20.10	Assigned
4qlqI00	20 Aug, 2014	3.60.20.10	Assigned
4qlqJ00	20 Aug, 2014	3.60.20.10	Assigned
4qlqK00	20 Aug, 2014	3.60.20.10	Assigned
4qlqL00	20 Aug, 2014	3.60.20.10	Assigned
4qlqM00	20 Aug, 2014	3.60.20.10	Assigned
4qlqN00	20 Aug, 2014	3.60.20.10	Assigned
4qlqO00	20 Aug, 2014	3.60.20.10	Assigned
4qlqP00	20 Aug, 2014	3.60.20.10	Assigned
4qlqQ00	20 Aug, 2014	3.60.20.10	Assigned
4qlqR00	20 Aug, 2014	3.60.20.10	Assigned
4qlqS00	20 Aug, 2014	3.60.20.10	Assigned
4qlqT00	20 Aug, 2014	3.60.20.10	Assigned
4qlqU00	20 Aug, 2014	3.60.20.10	Assigned
4qlqV00	20 Aug, 2014	3.60.20.10	Assigned
4qlqW00	20 Aug, 2014	3.60.20.10	Assigned
4qlqX00	20 Aug, 2014	3.60.20.10	Assigned
4qlqY00	20 Aug, 2014	3.60.20.10	Assigned
4qlqZ00	20 Aug, 2014	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1