PDB Information

PDB4QL1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Pharmacological targeting of the Wdr5-MLL interaction in C/EBP alpha N-terminal leukemia.
Grebien, F., Vedadi, M., Getlik, M., Giambruno, R., Grover, A., Avellino, R., Skucha, A., Vittori, S., Kuznetsova, E., Smil, D., Barsyte-Lovejoy, D., Li, F., Poda, G., Schapira, M., Wu, H., Dong, A., Senisterra, G., Stukalov, A., Huber, K.V., Schonegger, A., Marcellus, R., Bilban, M., Bock, C., Brown, P.J., Zuber, J., Bennett, K.L., Al-Awar, R., Delwel, R., Nerlov, C., Arrowsmith, C.H., Superti-Furga, G.
Nat.Chem.Biol.
HeaderTranscription/Inhibitor
Released2014-06-10
Resolution1.500
CATH Insert Date04 Jan, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Jan, 2015 Chopped
B 05 Jan, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ql1A00 08 Jan, 2015 2.130.10.10 Assigned
4ql1B00 10 Jan, 2015 2.130.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
P61964 WDR5_HUMAN Homo sapiens WD repeat-containing protein 5
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